Comprehensive wellness,
on your body’s terms

Nutrition, Exercise, Endocrinology all under one roof in New York City collaborating on your plan towards improved health and wellbeing.

  • Founded by Dr. Anastasios Manessis: double board-certified endocrinologist

We start with data, then work together to craft a plan
fully personalized to your body’s needs

Your baselineSample report
Resting metabolic rate
1,847kcal/day
Body fat
24.3%
Muscle mass
68.4lb
Vitamin D
32ng/mL
DEXA ScanBone density + body comp
Lab workHormones + metabolism

Women's Wellness * Pre-Diabetes * Insomnia * Type 1 Diabetes * Hashimoto's * Type 2 Diabetes * Gestational Diabetes * Thyroid Balance * Osteoporosis * Osteopenia *Hyperthyroidism * Hypothyroidism * Weight Loss * GLP-1 Support * Sleep Optimization * PCOS/PMOS * Sports Optimization * Longevity * Menopause * Perimenopause * Bone Health * General Health * Obesity *

Women's Wellness * Pre-Diabetes * Insomnia * Type 1 Diabetes * Hashimoto's * Type 2 Diabetes * Gestational Diabetes * Thyroid Balance * Osteoporosis * Osteopenia *Hyperthyroidism * Hypothyroidism * Weight Loss * GLP-1 Support * Sleep Optimization * PCOS/PMOS * Sports Optimization * Longevity * Menopause * Perimenopause * Bone Health * General Health * Obesity *

As featured on
Targeted analysis

What we measure before anything gets planned

Fully holistic. Fully personalized.

Every plan here starts with targeted analysis. Body composition, bone density, lab work, and resting metabolic rate give your care team a clear read on where your health stands. Your wellness plan is built from those results, then adjusted as your numbers change.

Shop all wellness plans + testing

Nutrition

Exercise

Endocrinology

neXendo is named for the three things we specialize in combining. Most people get sent to those three separately and end up managing the handoffs themselves, carrying their own results between offices that never compare notes.

We put all three in one place and give them one set of your data to work from

Why people come here

A doctor, a dietitian, and a trainer who share one set of your numbers

Most people are running two appointments and a gym membership that never talk to each other. Here is what sits under one roof at neXendo instead.

Ten rows. Scroll inside the table to read them all.

How neXendo Wellness compares with a standard doctor visit and a standard gym, across ten parts of care.
What you get neXendo Wellness Standard doctor visit Your gym
Hormone and metabolic lab work neXendo WellnessYesOrdered and read by an endocrinologist before any plan is written. Standard doctor visitSometimesDepends on the visit and the reason you came in. Your gymNoNot offered.
Resting metabolic rate testing neXendo WellnessYesMeasured directly, so your calorie number is yours rather than a formula's. Standard doctor visitNoNot part of a standard visit. Your gymSometimesSome gyms offer it, without clinical review of the result.
Body composition analysis neXendo WellnessYesBody fat, muscle mass, and how both move over time. Standard doctor visitSometimesUsually weight and BMI only. Your gymSometimesOften a handheld device or a smart scale.
Bone density scanning neXendo WellnessYesDEXA on site in Long Island City, read in context with your labs. Standard doctor visitSometimesReferred out, and the result often comes back without a plan attached. Your gymNoNot offered.
A written plan built from your own test results neXendo WellnessYesNutrition and training are written after the numbers come back, not before. Standard doctor visitSometimesAdvice in the room, rarely a document you leave with. Your gymSometimesA workout plan, built without any of your test results.
Registered dietitians who work across disease states neXendo WellnessYesOn staff, and reading the same results your doctor is. Standard doctor visitSometimesA referral out, if the practice has someone to refer to. Your gymNoNutrition coaching is not the same credential.
Supervised exercise neXendo WellnessYesLed by our medical fitness trainers, working with your doctor. Standard doctor visitNoYou are told to exercise, not shown how. Your gymYesNo medical data behind the session.
Care for chronic conditions neXendo WellnessYesDiabetes, thyroid, bone health, PCOS and menopause, all in one place. Standard doctor visitYesThe medical side, with nutrition and exercise handled elsewhere. Your gymNoNot a clinical setting.
Retesting, with the plan adjusted as your numbers move neXendo WellnessYesThe plan changes when the data does. Standard doctor visitSometimesAt the next annual, if you book one. Your gymNoNothing clinical is being tracked.
Insurance, FSA and HSA, or self-pay neXendo WellnessYesWe verify your coverage before your first visit, so you know the cost going in. Standard doctor visitYesCovered, for the medical portion. Your gymNoMembership and training come out of pocket.

This compares categories of care, not any named practice or gym. What a given doctor's office or gym offers varies, and plenty do more than the middle and right columns describe.

Did you know that you can actually rebuild bone density?

Bone is living tissue, and loading it is what tells it to hold on to density. ONERO® is a resistance and impact program built around that, offered at neXendo Wellness for people managing low bone density. We run it inside the practice, so whoever writes your progression can see your scan and your labs instead of guessing. Every session is supervised.

See how ONERO works

Listen Up

Come learn with us!

Listen to our monthly podcast, tune in on social media for weekly insights from our nutrition and fitness teams, and read a backlog of helpful deep-dives on our blog.

Abigail lost more than 80 pounds. Her A1C came down with it.

“This program did not just help me work out. It helped me change my life.”

Abigail, neXendo patient

Abigail came to us after a diabetes diagnosis in 2023.

Read Abigail’s story